-The at age above seventeen years old ,

-The medical economic journal find cost of illness for multiple sclerosis in health care in between 8,500$ and 50,000$ and increase every year ( the normal cost of illness from 8,000$ to 11,000$ and recently the cost of treatment about 60,000$ annually )
-recently , the new drug amended for treatment cost for multiple sclerosis is commonly enter market domain between 25 – 60% and higher from the available drug amended treatment – direct medical cost& the indirect medical cost represent 93.1% 6.9% outside from the total costs
– direct medical costs of multiple sclerosis is range from less than 15,000$ to higher than 50,000$ annually
-indirect medical costs are different from 3726$ to 19264$
(cost of outpatient visit is 3,443$ ,The prescription (DMC):it is cost is 1,834$ and The set back of inpatient hospitslization:1,546$ )
-the set back of treatment of patient with multiple sclerosis does not work increase around 3.3 fold and days pushed in bed increase around 4.4 folds
the cost of illness in Egypt :
-multiple sclerosis occur at age above seventeen years old , it is pervasive between 13,07-100,000 from each neurological illness ,
-the patient number infected by multiple sclerosis about approximately above 40,000 patient
At ain shams university , the head of neurology department : doctor samira ashour said that: patient who have treatment is cost from 2,000 EGP to 3,000 EGP for 3-6 month for treatment
-it was unfortunately some people are unable to buy for treatment because it is cost is high around 4,000 EGP that make them unable to continuous treatment
the Encharge of illness in united statue (us) :
-the set back of illness with multiple sclerosis in 2008-2012 was 4 billion is nearly 9 billion per year, In US we can obtain the average price per year for multiple sclerosis.
-They do much studies while the most known 15 studies include 2 group 8 studies who presented on direct cost calculated and the other group 7 studies who presented on total cost MS reported through these studies include direct and indirect cost from 8528 to 54,244 patient per year on average direct cost 77% ranged 64-91%of total cost and indirect cost 23% ranged 9-36% of total cost.
-in year 1990: the set back of illness of multiple sclerosis is approximately from 9,000$ to 12,000$ per patient per year , the cost of agent go on developing in addition to increasing in price
-in year 2004 :the range of burden for a sick was 16,050$ , THE total cost of care and exploit of service increase not only with high and good effect but also with increasing cost range in health care ; the cost for moderate relapse intensity function and lack of ability is 30,000$ and with high relapse intensity and inability 50,000$ and with sever inability cost 100,000$.
-in year 2012: average patient price of illness was 30,000$ annually
In middle east : (multiple sclerosis exiting in 5 eastern countries)
The diffusion of disease observed increasing significantly in recent decade with faster rate between female and male. Interferon was the most treatment use in the middle east and Egypt and MRI scanner lower use in the middle east they need more research about other treatment.
-in worldwide : multiple sclerosis affect around 2.5 million patient


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