Scanlon, Wells, Woolforde, Khameraj, and Baumgarten (2017) developed a catheter associated urinary tract infection (CAUTI) reduction program, focusing on developing the best practices for CAUTI prevention. The study consisted of 188 registered nurses who were the CAUTI ambassadors, also known as the “Clinical Army.” These individuals ranged from hospital chief nursing officer, chief medical officer, chief quality office, advanced practice providers, infection prevention, nursing education, frontline nursing leadership, and clinical staff such as registered nurses, physicians, patient care associates, physical therapist, patient transporters, and technicians. Each of the CAUTI ambassadors completed education and validation on insertion techniques with return demonstration on mannequins. In addition they received training on perineal care, maintenance of drainage bags below the level of bladder, two-RN mandate for insertion time out, and lastly a “Train the Trainer” model to validate staff on new protocols. The results included a significant decrease in ICU CAUTI measures defined as ICU CAUTI standardized infection ratio (SIR), ICU CAUTI incidence, ICU catheter days, and cost impact. The study began in 2013, continuing through 2014 (12 months) and concluding June of 2015 (18 month period). Over the 12-month period, there was a decline in ICU SIR of 32% and in 18 months showed a 73% reduction. ICU CAUTI incidence decreased by 46% and 89%, while catheter days decreased by 22% and 58% respectively. Also, ICU catheter days dropped 11% and 56% respectively. As a result, there is a significant decrease in CAUTIs with the use of the CAUTI reduction program. Nurses not only can increase their education on urinary catheters as well but also, improve patient care.