Our shown a strong link between obesogenic

Our society has experienced a large spike in obesity worldwide alongwith its associated disorders. While sedentary lifestyles and excess calorieintake have gotten must of the bad wrap, our microbiota hasn’t been getting any!The truth is, studies have shown a strong link between obesogenic diets and thenegactive impact it plays on our microbiomes. “Changes in diet can account for57% of the variations in microbiota.

” A study was conducted by Turnbaugh et al.on mice gavaged with human feces to study the correlation between diet and thehuman microbiota. The study consisted of two groups of mice—one group fed avegetarian diet and the other a western diet consisting of high-fatty foods.Results proved that the mice fed with the western diet had increased numbers ofbacteria associated with the Firmicutesphyla and a large decrease in one of the four most dominant bacterial phyla in thehuman gut–Bacteroides spp. The shiftin gut community for mice being fed the Western diet was evident, so much so,scientists were able to notice within a day.

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So what? We get a new phyla of gut bacteria with a new diet—but whatharm can the change of composition of a microbe do to our bodies?It’s important to really consolidate the fact that gut bacteriasuch as the Bacteroides spp. are dominant for a reason, they are meant to regulatecertain processes in the body and any change in composition to the naturalorder in which our body is meant to run can mean serious implications on ourhealth. Here’s why….The Bacteroides spp. is responsible for producing GLP-2, anintestinal peptide that prevents lipopolysaccharide (LPS) from entering ourplasma by protecting the gut and making sure food is digested properly.

Withdecreased levels of GLP-2 caused by the Firmicutesphyla, we are likelier to get higher levels of LPS plasma concentration andwhat we now know as a “leaky gut”. Aleaky gut can translate to serious health complications, as the increasedpermeability of the gut (the “leakiness”) may permit toxins to flow out of ourintestines and into our blood stream!It is important we keep ourselves properly informed on howobesogenic diets affect not just our weight and energy levels but also ourmicrobiomes. A simple change in the composition of our microbes can be one ofthe leading resulting causes of disease in obese individuals.


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